Cancer Specialists Hold New Tools in Treatment for Mesothelioma, though Prognosis Looks Grim

Cancer doctors choose what kind of treatment to pursue for their patient. The options are endless. There are no universal treatment regimen for malignant mesothelioma sufferers. This is due to the cancers high mortality rate, rareness, low treatment success rate, and small number of studies to provide meaningful statistics.

The prospects for mesothelioma patients have been grim, but doctors have recently made progress. Treatments for cancer are traditionally surgery (taking out the tumor and surrounding tissue), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) All three methods have problems. Patients with mesothelioma have not responded well to traditional radiation therapy. In hopes to lessen damage to healthy tissue, researches are studying ways to aim radiation right at the tumor.

Surgery removes the mesothelial tissue around the tumor. The surgery is difficult and challenging, with unknown effects or benefits to patients. Most chemotherapy medication that work on other cancers typically do not work on mesothelioma, and combinations of chemotherapy agents have been tried, but without much success. Like radiation, researchers are focusing their work on controlling the physical location of the treatment with an emphasis on the pleural cavity.

The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. These include biologic therapy such as the agent interleukin 2 and anti-angiogenesis drugs such as thalidomide. Pemetrexed (Alimta) is a new drug that has shown results in extending life.

Oncologists consider the stage of mesothelioma, the location of the tumor, the patient’s age and state of health at the time. Two exotic ways of attacking mesothelioma are gene therapy and photodynamic therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.

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